![白雪岭](/uploads/img1/20230804/64cca89bb1e54.jpg)
白雪岭
高级工程师、博导
研究领域:骨科生物力学与器械;3D打印技术在医疗领域应用
邮箱:xl.bai@siat.ac.cn
- 个人简介
- 代表性项目
- 代表性成果
- 团队成员
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白雪岭(Bai ,Xuling),博士,高级工程师,博士生导师,中科院深圳先进技术研究院。深圳市高层次专业人才,南山区领航人才。广东省自然科学基金委评审专家,深圳创新委评审专家。国际华人骨研协会会员、中国研究型医院学会骨科创新与转化专业委员会数字骨科组委员、SICOT中国部数字骨科学会广东省分会委员、中国医学装备学会医用增材制造专委会委员、广东省医学会数字医学分会委员、广东省转化医学学会会员、深圳市医学会关节外科青年委员会委员、深圳市保健科技学会骨质酥松专业委员会委员等。Journal of Orthopaedic Translation、Computer Methods in Biomechanics and Biomedical Engineering、Clinical Biomechanics、Engineering、医用生物力学等期刊审稿专家。白雪岭博士主持/参加国家、地区15余项,发表学术论文60余篇,申请专利20余项,撰写科学专著2部,获2021年度广东省技术发明二等奖“3D打印个性化骨缺损修复植入体关键技术与临床应用”。
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部分科研项目:
1)深圳市技术攻关项目,400万,重20180084 基于钛合金材料的颅颌面缺损修复关键技术研发,2019.1-2020.12
2)深圳市基础研究学科布局项目,200万,基20170486个性化植入假体金属3D打印关键技术与临床应用研究,2018.1-2020.12
3)深圳市技术攻关项目,300万,重20170649个性化骨折固定夹板快速成型系统研发,2018.1-2019.12
4)深圳市基础研究,30万,3D打印关键技术:基于影像引导的可控渐变孔隙率多孔结构3D建模技术研究,2015.10-2017.9
5)深圳市技术开发项目,200万,新型复合生物活性骨修复材料关键技术研发,2015.10-2017.9
6)深圳市基础研究学科布局,300万,基于3D打印技术的骨修复材料研究,2015.10-2017.9
7)国家自然科学基金:基于微观结构和电偶腐蚀的生物可降解镁合金腐蚀过程建模与仿真研究, 2013.01-2015.12
8)深圳发改委, 300万, 深圳市个性骨科技术与制造服务平台, 2012.01-2013.12
9)深圳国际科技合作项目, 50万, 表面改性多节段转角自适应型颈椎人工椎间盘产业化关键技术研发, 2012.01-2013.12
10)深圳发改委, 465万, 深圳医用生物活性材料工程实验室, 2012.01-2014.12
11) 国家高新技术863项目:系统生物信息共享平台及特色数据库构建(863计划:2003AA231011)。
12) 国家高新技术863项目:数字化虚拟人体若干关键技术(863计划:2004AA231030)。
13) 国家自然科学基金面上项目:基于术后骨重建过程仿真与远期骨态预测的骨关节假体设计原理与方法研究(30470455)。
14)国家自然科学基金重点项目:中国力学虚拟人(30530230),整体小组负责人
15)国家自然科学基金重大国际合作项目:亚洲人种髋、膝关节特性研究与人工髋、膝关节基本设计(30810103908)
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【专著】
1. 主编: 王成焘, 副主编:王冬梅, 白雪岭, 王建平, 唐钢, 人体骨肌系统生物力学, 科学出版社, 2015.9
2. 主编: 王成焘, 苏秀云 副主编: 白雪岭, 陈晓军, 李严兵等, 数字骨科学基础(数字骨科学丛书, 总主编:裴国献), 山东科学技术出版社, 2019.2
【申请专利】
1. 白雪岭, 深圳先进技术研究院. 软件著作权:基于影像引导的类松质骨多孔结构3D建模软件V1.0.登记号:2017SR479438.
2. 白雪岭,3D多孔支架模型建立方法、装置及制备系统, 中国发明专利号, 201711239691.0, 申请日:2017-7-27.
3. 方国芳、桑宏勋、白雪岭,一种膨胀式融合器,中国实用新型专利号, 201720282701.8, 申请日:2017-3-22.
4. 黄曹、易伟宏、白雪岭,颈部肌群功能锻炼辅助装置与系统, 中国发明专利号, 201610984684.2, 申请日:2016-11-09.
5. 黄曹、易伟宏、白雪岭,颈部肌群功能锻炼辅助装置与系统, 中国实用新型专利号, 201621208294.8, 申请日:2016-11-09.
6. 陈晓东, 白雪岭, 椎间盘的纤维环用修补器, 中国发明专利号, 201410853395.X , 公开日: 2016-07-27.
7. 尚鹏, 白雪岭, 卢俊哲, 一种人工膝关节, 中国发明专利号, CN 102793594A, 授权公告日:2015.11.18.
8. 陈晓东, 白雪岭, 椎间盘的纤维环用修补器, 中国实用新型专利号, CN 204542325U, 授权公告日: 2015.08.12.
9. 陈晓东, 白雪岭, 经椎弓根置入导向器, 中国实用新型专利号, CN 204318891U, 授权公告日:2015.05.13.
10. 尚鹏、白雪岭, 脊椎内固定装置, 中国发明专利号, CN 103190948A, 授权公告日:2015-06-03.
11. 尚鹏, 白雪岭, 卢俊哲, 人工髋关节, 中国发明专利号, CN 102813565A, 授权公告日:2015.02.25.
12. 尚鹏, 白雪岭, 李军, 陈扬.椎间融合器, 中国发明专利号, CN102488574A, 授权公告日:2014.12.24.
13. 尚鹏、张黎楠、白雪岭、叶新、田岚、耿艳娟, 人工髋关节结构 , 中国实用新型专利号, CN 203609546 U, 授权公告日: 2014.05.28.
14. 尚鹏、张黎楠、白雪岭、叶新、田岚、耿艳娟, 髌骨假体结构, 中国实用新型专利号, CN 203576699 U, 授权公告日:2014.05.07.
15. 尚鹏, 白雪岭, 张黎楠, 叶新, 黄旭, 侯增涛, 许兆斌, 髌骨组织工程支架, 中国实用新型专利号, CN 203263590U, 授权公告日:2013.11.06.
16. 尚鹏, 白雪岭, 张黎楠, 叶新, 黄旭, 侯增涛, 许兆斌, 髌骨组织工程支架及其制造材料和制备方法 , 中国发明专利号, 201310098217.6, 授权公告日:2013.03.26.
17. 尚鹏, 白雪岭, 李军, 陈扬, 椎间融合器 , 中国实用新型专利号, CN 202386760U, 授权公告日:2012.08.22.
【代表性论文】
[1] Xiyue Zhang, Hui Liu, Ling Li, Cuishan Huang, Xiangbo Meng, Junzuo Liu, Xueling Bai, Ling Ren, Xinluan Wang, Ke Yang1, and Ling Qin. Promoting osteointegration effect of Cu-alloyed titanium in ovariectomized rats. Regenerative Biomaterials, 2022, 9, rbac011
[2] Ruliang Feng, Huiren Tao, Canhua Ye, Guanglin Li, Xueling Bai, Lin Wang. A quantitative biomechanical study for precise orthopedic intervention in idiopathic scoliosis. IEEE RCAR 2022.
[3] Wen-Xiang Cheng; Huan Huang;Jian-Hai Chen; Tian-tian Zhang; Guo-Yuan Zhu; Zheng-Tan Zheng; Jie-Tao Lin; Yi-Ping Hu; Yong Zhang; Xue-Ling Bai; Yan Wang; Zhan-Wang Xu; Bing Song; Yi-Ying Mao; Fei Yang;Peng Zhang. Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signaling pathway. Journal of Orthopaedic Translation, Volume 22, May 2020, Pages 92-100
[4] Y Hu,T Zhang,J Chen,WX Cheng,J Chen,Z Zheng,J Lin,G Zhu,Y Zhang,X Bai. Downregulation of Hypoxia-Inducible Factor-1α by RNA Interference Alleviates the Development of Collagen-Induced Arthritis in Rats Molecular Therapy — Nucleic Acids, Volume 19, 6 March 2020, Pages 1330-1342.
[5] Yiping Hu, Tiantian Zhang, Huan Huang, Wenxiang Cheng, Yuxiao Lai, Xueling Bai, Jianhai Chen, Ye Yue, Zhengtan Zheng, Chengshan Guo, Ling Qin. Fracture healing in a collagen‐induced arthritis rat model: Radiology and histology evidence. J Orthop Res. 2018 Nov;36(11):2876-2885
[6] Jiali Wang; Yuanhao Wu; Huafang Li; Yang Liu; Xueling Bai; Wingho Chau; Yufeng Zheng; Ling Qin. Magnesium Alloy based Interference Screw Developed for ACL Reconstruction Attenuates Peri-Tunnel Bone Loss in Rabbits, Biomaterials, 2018,157: 86-97.
[7] Bai Xueling, Peng Ding, Zhang Peng, Yao Zhidong. Research on Modeling of Bionic Porous scaffold for bone defect repair based on Bone Mineral Density Distribution. Advances in Intelligent Systems Research, 2018, 151:30-33
[8] Xueling Bai, Peng Shang, “The Biomechanics Analysis of Anatomical Morphology of Skeleton,” IEEE-EMBS International Conference on Biomedical and Health Informatics. 2012: 836-839
[9] Shang Peng, Bai Xueling, “A Non-linear contact FE Model to Evaluate Pressure Ulcer on Buttock-thigh under Sitting,” IEEE-EMBS International Conference on Biomedical and Health Informatics. 2012: 748-751
[10] Peng Shang*, Xueling Bai. An ultrasound approach to digitizie bony landmarks in navigation assisted total hip arthroplasty. The 2013 6th International Congress on Image and Signal Processing, 2013: 342-346
[11] X. Ye, L. Zhang, Z. Xu, Z. Hou, X. Bai, and P. Shang, "Effect of Suture Density on the Dynamic Behavior of the Bioprosthetic Heart Valve: A Numerical Simulation Study," in Health Information Science. vol. 8423, Springer International Publishing, 2014, pp. 29-39.
[12] X. Ye, L. Zhang, Z. Xu, Z. Hou, X. Bai, and P. Shang, "Numerical Evaluation of the Effectiveness of the Air Chamber of Shoes Pad for Diabetes with FE-SPH Method," in Health Information Science. vol. 8423, Springer International Publishing, 2014, pp. 20-28.
[13] Shang Peng, Zhang Linan, Hou Zengtao, Bai Xueling, Ye Xin, Xu Zhaobin, Huang Xu. Morphometric measurement of the patella on 3D model reconstructed from CT scan images for the southern Chinese population. Chin Med J. 2014 , 127 (1) :96-101
[14] Li-Nan Zhang, Zeng-Tao Hou, Xin Ye, Zhao-Bin Xu, Xue-Ling Bai, Peng Shang. The effect of selected alloying element additions on the properties of the Mg-based alloy as bioimplants: A literature review. Frontiers of materials science. 2013, 7(3): 227–236
[15] Bai Xueling, Yu Li, Liu Qian, Zhang Jie, Li An’an, Han Dao, Luo Qingming, Gong Hui. A High-Resolution Anatomical Rat Atlas. J Anat., 2006, 209(5): 707-708.
[16] Bai Xueling, Wei Gaofeng, Ye Ming, Wang Dongmei, Hu Yan, Liu Zongliang, Nie Wenzhong, Zhang Linlin, Ji Wenting, Li Yunting, Wang Chengtao. Finite Element Musculoskeletal Modeling of Mechanical Virtual Human of China. ICBBE 2008, 1847-1850.
[17] Bai Xueling, Liu Qian, Yu Li, Liao Yinping, Luo Qingming, Gong Hui. The Development of Small Laboratory Animal Atlas, Conf Proc IEEE Eng Med Biol Soc., 2005, 2(1):1472-1475.
[18] Bai Xueling, Zhang Xi’an, Wang Hongsheng, Ji Wenting, Wang Chengtao. Three-dimension Kinematics Simulation and Biomechanics Analysis of Snatch Technique. IACSS, SBSP 2008, 2008, 1: 291-296.
[19] Bai Xueling, Shang Peng, Wang Chengtao. Distribution features of stress-strain, principle stress vectors and displacements of normal femur during gait. CRTER, 2010, 14(52): 9873-9876.
[20] Wei Gaofeng, Bai Xueling, Wang Hongsheng, Fu Zengliang, Wang Chengtao. Component mode synthesis approach to estimate tibial strain. Journal of Medical Engineering and Technology, 2009, 33(6): 488-495.
[21] Yu Li, Liu Qian, Bai Xueling, Liao Yinping, Luo Qingming, Gong Hui. A Digital Rat Atlas of Sectional Anatomy. Fourth International Conference on Photonics and Imaging in Biology and Medicine, 2006, 6047:60470Y1-7.
[22] Hu Kongzu, Zhang Xianlong, Zhu Junfeng, Wang Chengtao, Ji Wenting, Bai Xueling. Periprosthetic fractures may be more likely in cementless femoral stems with sharp edges. Ir J Med Sci, 2010, 179:417-421.
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