科研队伍

Antonia Sun, 博士后。 2019年于Queensland University of Technology （Brisbane, Australia）获得博士学位，同年9月份加入中国科学院深圳先进技术研究院。研究领域 （1）The role of macrophage-mediated synovitis in obesity-associated osteoarthritis; (2) The development of innovative therapeutic strategies targeted at osteoarthritis-synovitis。 目前发表SCI 论文5篇，会议摘要1篇。

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【代表性成果】

1.       Sun, A. R., Friis, T., Sekar, S., Crawford, R., Xiao, Y., & Prasadam, I. (2016). Is Synovial Macrophage Activation the Inflammatory Link Between Obesity and Osteoarthritis? Current Rheumatology Reports, 18(9), 57. doi:10.1007/s11926-016-0605-9

2.       Sun, A. R., Panchal, S. K., Friis, T., Sekar, S., Crawford, R., Brown, L., . . . Prasadam, I. (2017). Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis. PLOS ONE, 12(8), e0183693. doi:10.1371/journal.pone.0183693

3.       Sun, A. R., Wu, X., Liu, B., Chen, Y., Armitage, C. W., Kollipara, A., . . . Prasadam, I. (2019). Pro-resolving lipid mediator ameliorates obesity induced osteoarthritis by regulating synovial macrophage polarisation. Scientific Reports, 9(1), 426. doi:10.1038/s41598-018-36909-9

4.       Sun, A., Xiao, Y., & Prasadam, I. (2017). High dietary cholesterol level induced metabolic overload cause osteoarthritis-like changes of the cartilage and shift macrophage polarization status in a mouse model. Osteoarthritis and Cartilage, 25, S404-S405. doi:10.1016/j.joca.2017.02.697

5.       Showiheen, S. A. A., Sun, A. R., Wu, X., Crawford, R., Xiao, Y., Wellard, R. M., & Prasadam, I. (2019). Application of Metabolomics to Osteoarthritis: from Basic Science to the Clinical Approach. Current Rheumatology Reports, 21(6), 26. doi:10.1007/s11926-019-0827-8

6.       Wu, X., Showiheen, S. A. A., Sun, A. R., Crawford, R., Xiao, Y., Mao, X., & Prasadam, I. (2019). Exosomes Extraction and Identification. In J. Batra & S. Srinivasan (Eds.), Theranostics: Methods and Protocols (pp. 81-91). New York, NY: Springer New York.